July-September 2021 Issue

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Role of local installation of Vancomycin powder for Prophylaxis against Infection in open fracture

Rajesh k Dulani1, S Rawate2, R Sadani3, Deepak G4, Bodhan parate5
1- Professor, 2- Assistant Professor, 3- Assistant Professor, 4- Assistant Professor, 5- Senior Resident, Department of Orthopaedics, Bharat Ratna Late Shree Atal Bihari Vajpai Memorial Medical College, Rajnandgaon (CG)

Abstract

Open fractures are known to be high risk for infection, even when treated with thorough debridement, stabilization, and appropriate systemic antibiotic therapy. Infection rates can be divided on the basis of Gustilo-Anderson fracture type-1, although there is variation in the literature, with rates of 0% to 6% for type-I fractures, rates of 2% to 6% for type-II fractures, and rates of 5% to 50% for type-III fractures Systemic antibiotics substantially lower infection rates in open fractures. Wound cavities are avascular; therefore, systemically administered antibiotics only achieve low concentrations in the fluids that collect in the cavity The purpose of this study was to determine the efficacy of local wound cavity installation of Vancomycin in conjunction with systemic antibiotics, to lower the prevalence of infection in patients with open fractures. This study suggests that local installation of Vancomycin administration as an adjunct to systemic antibiotics may be effective in lowering infection rates in open fractures; further research with higher-level research designs is needed.

Healthy Diet leads to Healthy Body and Healthy Mind

Anantprakash S. Saraf1, Kanchi A. Saraf2
1- Assistant Professor (Psychiatry), BRLSABVM Government Medical College, Rajnandgaon, Chhattisgarh. 2- Department of Hospital Management, Jiwaji University, Gwalior, Madhya Pradesh

ABSTRACT

Nutrition and Health are the most important contributory factors for human resource development in the country. Unhealthy diet and poor nutrition have been associated with poor mental and physical health. Evidence from dietary intervention studies indicates an improvement of both physical and mental health through healthy diet. This article comprehensively reviews literature on this subject.

Microbial signatures as a predictive tool in health and disease

Ramanesh Murthy, Dean and Director Professor, Director Professor, Department of Microbiology, GMC, Ambikapur (C.G) 497001

ABSTRACT

This article is a comprehensive review of literature on the use of microbial signatures as a predictive tool in various aspects of science and its applications in daily life.

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